Rune Transmutation Revision: October 26, 2021
Rune transmutation combines two different runes of the same tier into another rune of that tier. The order of the two input runes does not matter.
- Combine two different runes of the same tier according to the tables below.
- Combine five identical runes of the same tier to create one rune of the next tier.
Block and Shield do not have a direct two-rune recipe in the current game data. As a result, recipes that require them are practically available from Tier X. Experience and Loot are disabled.
For drillers, extraction, Item Shop runes and drop rates, see Runes.
Rank 0 Runes
| Rune | Highest Tier | Transmutation (Same Tier) | Notes |
|---|---|---|---|
 [Defense I] |
 [Defense XIII] |
 [Quickness I] +  [Resistance I] |
— |
 [Endurance I] |
 [Endurance XIII] |
[Defense I] + [Resistance I] |
— |
 [Harm I] |
 [Harm XIII] |
 [Mind I] +  [Vigor I] |
— |
 [Magic I] |
 [Magic XIII] |
 [Shell I] +  [Vitality I] |
— |
| [Mind I] |
 [Mind XIII] |
 [Strike I] + [Vitality I] |
— |
| [Quickness I] |
 [Quickness XIII] |
[Mind I] + [Resistance I] |
— |
| [Resistance I] |
 [Resistance XIII] |
[Vigor I] + [Quickness I] |
— |
| [Shell I] |
 [Shell XIII] |
[Magic I] + [Vitality I] |
— |
| [Strike I] |
 [Strike XIII] |
[Magic I] + [Mind I] |
— |
| [Vigor I] |
 [Vigor XIII] |
[Resistance I] + [Vitality I] |
— |
| [Vitality I] |
 [Vitality XIII] |
[Shell I] + [Mind I] |
— |
Rank 1 Runes
| Rune | Highest Tier | Transmutation (Same Tier) | Notes |
|---|---|---|---|
 [Atonement I] |
[Atonement XIII] |
[Endurance I] + [Resistance I] |
— |
 [Charm I] |
 [Charm XIII] |
 [Intellect I] +  [Spell I] |
— |
 [Cruelty I] |
 [Cruelty XIII] |
[Intellect I] +  [Savage I] |
— |
 [Dexterity I] |
 [Dexterity XIII] |
 [Stamina I] + [Intellect I] |
— |
 [Excite I] |
[Excite XIII] |
[Vitality I] + [Vigor I] |
— |
 [Guts I] |
[Guts XIII] |
[Magic I] + [Resistance I] |
— |
| [Intellect I] |
 [Intellect XIII] |
[Charm I] +  [Spirit I] |
— |
 [Life I] |
 [Life XIII] |
 [Safeguard I] + [Stamina I] |
— |
 [Payback I] |
[Payback XIII] |
[Vitality I] + [Mind I] |
— |
 [Rouse I] |
[Rouse XIII] |
[Endurance I] + [Quickness I] |
— |
| [Safeguard I] |
 [Safeguard XIII] |
[Stamina I] + [Dexterity I] |
— |
| [Savage I] |
 [Savage XIII] |
[Stamina I] + [Spirit I] |
— |
| [Spell I] |
 [Spell XIII] |
 [Ward I] + [Spirit I] |
— |
| [Spirit I] |
 [Spirit XIII] |
[Ward I] + [Intellect I] |
— |
| [Stamina I] |
 [Stamina XIII] |
[Dexterity I] + [Savage I] |
— |
 [Triumph I] |
[Triumph XIII] |
[Endurance I] + [Mind I] |
— |
| [Ward I] |
 [Ward XIII] |
[Spell I] + [Spirit I] |
— |
Rank 2 Runes
| Rune | Highest Tier | Transmutation (Same Tier) | Notes |
|---|---|---|---|
 [Anger I] |
[Anger XIII] |
[Triumph I] + [Excite I] |
— |
 [Barrier I] |
[Barrier XIII] |
[Triumph I] + [Guts I] |
— |
 [Capability I] |
 [Capability XIII] |
[Spell I] + [Stamina I] |
— |
 [Comprehension I] |
 [Comprehension XIII] |
[Life I] + [Intellect I] |
— |
 [Devil I] |
 [Devil XIII] |
[Spirit I] + [Intellect I] |
— |
 [Ferocity I] |
 [Ferocity XIII] |
[Life I] + [Stamina I] |
— |
 [Grasp I] |
 [Grasp XIII] |
[Spirit I] + [Savage I] |
— |
 [Keenness I] |
 [Keenness XIII] |
[Dexterity I] + [Life I] |
— |
 [Mayhem I] |
[Mayhem XIII] |
[Guts I] + [Excite I] |
— |
 [Resistor I] |
[Resistor XIII] |
[Rouse I] + [Guts I] |
— |
Rank 3 Runes
| Rune | Highest Tier | Transmutation (Same Tier) | Notes |
|---|---|---|---|
 [Dauntlessness I] |
 [Dauntlessness XIII] |
[Comprehension I] + [Capability I] |
— |
 [Destruction I] |
 [Destruction XIII] |
[Grasp I] + [Capability I] |
— |
 [Enchantment I] |
 [Enchantment XIII] |
[Keenness I] + [Capability I] |
— |
 [Fearless I] |
[Fearless XIII] |
[Resistor I] + [Barrier I] |
Accessory rune |
 [Fountain I] |
[Fountain XIII] |
[Mayhem I] + [Resistor I] |
Accessory rune |
 [Madness I] |
 [Madness XIII] |
[Comprehension I] + [Grasp I] |
— |
 [Passion I] |
[Passion XIII] |
[Barrier I] + [Anger I] |
Accessory rune |
 [Potential I] |
[Potential XIII] |
[Mayhem I] + [Anger I] |
— |
Rank 4 Runes
| Rune | Highest Tier | Transmutation (Same Tier) | Notes |
|---|---|---|---|
 [Accuracy I] |
 [Accuracy XIII] |
[Dauntlessness I] + [Enchantment I] |
Weapon rune |
 [Agile I] |
[Agile XIII] |
[Fountain I] + [Passion I] |
— |
 [Curse I] |
 [Curse XIII] |
[Enchantment I] + [Destruction I] |
Weapon rune |
 [Enlightenment I] |
 [Enlightenment XIII] |
[Destruction I] + [Madness I] |
— |
 [Might I] |
[Might XIII] |
[Fearless I] + [Passion I] |
— |
 [Raid I] |
 [Raid XIII] |
[Dauntlessness I] + [Madness I] |
Weapon rune |
 [Sorcery I] |
[Sorcery XIII] |
[Fearless I] + [Fountain I] |
— |
Rank 5 Runes
| Rune | Highest Tier | Transmutation (Same Tier) | Notes |
|---|---|---|---|
 [Advance I] |
[Advance XIII] |
[Sorcery I] + [Might I] |
— |
 [Aggression I] |
[Aggression XIII] |
[Agile I] + [Might I] |
— |
 [Assassin I] |
 [Assassin XIII] |
[Raid I] + [Curse I] |
— |
 [Block X] |
[Block XIII] |
No direct two-rune recipe | First practical tier: X |
 [Revolution I] |
[Revolution XIII] |
[Sorcery I] + [Agile I] |
— |
 [Sage I] |
 [Sage XIII] |
[Curse I] + [Accuracy I] |
— |
 [Shield X] |
[Shield XIII] |
No direct two-rune recipe | First practical tier: X |
 [Tyrant I] |
 [Tyrant XIII] |
[Accuracy I] + [Raid I] |
— |
Rank 6 Runes
| Rune | Highest Tier | Transmutation (Same Tier) | Notes |
|---|---|---|---|
 [Enigma I] |
 [Enigma XIII] |
[Assassin I] + [Tyrant I] |
— |
 [Experience I] |
[Experience XIII] |
Disabled | Weapon rune Not available in game |
 [Hatred X] |
[Hatred XIII] |
[Block X] + [Aggression X] |
Weapon rune Crafting starts at Tier X |
 [Judge I] |
 [Judge XIII] |
[Sage I] + [Tyrant I] |
— |
 [Loot I] |
[Loot XIII] |
Disabled | Weapon rune Not available in game |
 [Massacre I] |
 [Massacre XIII] |
[Assassin I] + [Sage I] |
— |
 [Reconciliation X] |
[Reconciliation XIII] |
[Shield X] + [Advance X] |
Weapon rune Crafting starts at Tier X |